piRNAs meet mitochondria.
نویسندگان
چکیده
zuc/MitoPLD encodes a conserved enzyme that localizes to mitochondria and hydrolyzes the mitochondria-specific lipid cardiolipin. Surprisingly, zuc/MitoPLD activity is required for Piwi-interacting RNA (piRNA)-mediated silencing of transposable elements in fly and mouse germlines, suggesting that signaling from mitochondria influences the piRNA pathway.
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عنوان ژورنال:
- Developmental cell
دوره 20 3 شماره
صفحات -
تاریخ انتشار 2011